Amplify Bio

United States
Pre Seed
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About Amplify Bio

Amplify Bio is a venture capital firm based in United States, focusing on Pre-Seed stage investments. The fund actively supports founders building innovative solutions in SaaS, providing strategic guidance and capital to help startups scale.

Investment Focus

Location / RegionUnited States
Funding StagePre Seed
Industry Focus
Saas

Investor Signals Profile

active

Sweet Spot

Deep technical founders building AI, infra, or dev tools since 2012

technical founders
AI/ML infra
developer tools
vertical AI
seed/pre-seed
supply chain security
agent tooling
databases
onchain finance
bio/immune engineering

Bullish Signals

15 years backing top technical foundersexternal
Portfolio: Datadog, Runway, Temporal, dbtexternal
First investor for engineers & researchersexternal
Strong AI infra portfolio momentumexternal
New adds: Modal, Luma, Chainguard, Hightouchwebsite
Vertical AI thesis + $125M Avoca roundwebsite
Active content: bio, agent, GPU investingwebsite
Founder testimonials: Temporal, Scribe CEOswebsite
Deep technical writing signals portfolio accesswebsite
Robotics bet: Covariant in portfoliowebsite
New bets: TigerBeetle, CedarDB, Antithesiswebsite
Bio arm active: new advisors announcedwebsite
GPU/audio AI: Gradium, Kyutai investedwebsite
Agent toolchain thesis actively publishedwebsite
Moonbounce: new AI guardrails investmentwebsite
Cancer recurrence bio bet: Infinitopeswebsite
PicnicHealth, Hex in founder rosterwebsite
Supply chain security: Chainguard flagshipwebsite
Data platforms: Hightouch, agent harnesswebsite
Database innovation: TigerBeetle, CedarDB focuswebsite
2026 AI Engineering Report surveyed 1000+ engineerswebsite
Writing fellowship + onchain finance (Allium)website
Deterministic Simulation Testing (DST) prioritywebsite
Memory systems: Engram, Waypoint Bio investmentswebsite
Agent infrastructure: long-running harness, Git-like toolswebsite
Immune engineering & file systems for agentswebsite
Portfolio CEO quotes: Temporal, Scribe validationwebsite

Contrarian Signals

Narrow mandate: technical founders onlyexternal
GP names mostly opaque publiclyexternal
Bio arm adds scope beyond core thesiswebsite
No fund size or stage data disclosedwebsite
Expanding verticals: DB, bio, audio AIwebsite
Scope creep: onchain finance, writing, immune engwebsite

Founder Do's

Be an engineer, researcher, or scientist
Building infra, models, or dev tools
Show deep technical depth early
Open to hands-on partner involvement
Reference open source or research background
Share deep technical writing or research
Working on deterministic testing, agents, or memory systems

Founder Don'ts

Non-technical or sales-led founders
No late-stage or growth-only plays
Avoid pure GTM without technical moat

Key GPs & Partners

MI
Mike (Amplify)
Partner
founder-firsthands-ontrusted advisor
LE
Lenny (Amplify)
Partner
technicalearly-stagebuilder-focused

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Fund Overview

Fund Size$200M
Saves0

Key People

Elliot Hershberg

Mike (Amplify)Partner
Lenny (Amplify)Partner

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