2048 Ventures

United States
Pre Seed
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About 2048 Ventures

Thesis-driven pre-seed and seed fund focused on Vertical AI, Deep Tech, Healthcare, and Biotech. Leads early rounds with initial checks of $500K-$3M.

Investment Focus

Location / RegionUnited States
Funding StagePre Seed
Industry Focus
Ai Ml
Biotech
Deep Tech
Digital Health

Investor Signals Profile

active

Sweet Spot

Technical founder solving manufacturing/production bottlenecks in biotech or physical AI

vertical-AI
deep-tech
healthcare
biotech
pre-seed-lead
protein-manufacturing
physical-AI
space-tech
commercial-real-estate

Bullish Signals

Fund III oversubscribed at $82M, signalling strong LP conviction in thesisblog
Leads pre-seed rounds with meaningful checks before institutional capital arrivesblog
Rapid deployment process reduces founder waiting time significantlyblog
Live pitch competitions, $50K prizes per verticaltwitter
Portfolio CTO AI survey — active community engagementtwitter
Portfolio co wins Edison Award for Physical AItwitter
Biotech + Deep Tech Boston events May 27–28twitter
Healthcare + Vertical AI NYC event June 2twitter
Century Health founder interview — portfolio spotlighttwitter
Deadline extended — high founder demand for pitch eventstwitter
Laminar Edison Award — physical AI portfolio wintwitter
CTO AI survey signals deep portfolio engagementtwitter
Ranked Top 2% of 400+ early-stage deep tech fundstwitter
Portfolio exits: Nebex (Google Ventures $30M), fintech (Google Ventures backing)twitter
Protein manufacturing infrastructure emerging as key thesis focustwitter
Portfolio visibility: Airspace Link (counter-drone), Laminar (molecular AI)twitter
Portfolio wins: Propensity Inc5000 second year, Citruslabs Inc5000 second yeartwitter
Portfolio momentum: Fazeshift attracts Amex Ventures backingtwitter
Campus sourcing strategy — best companies emerge from student communitiestwitter
VC Fellowship Fall '26 — building next generation talent pipeline in Bostontwitter
Active NYC founder community events — expanding beyond Boston basetwitter
Space tech portfolio (Nebra Exchange) signals emerging vertical diversificationtwitter

Contrarian Signals

Rejects volume-based investing; only high-conviction bets consideredblog
Avoids short-lived tech trends without fundamental differentiationblog
Heavy event focus may slow direct founder outreachtwitter

Founder Do's

Show deep technical differentiation and defensible data moats
Highlight domain depth and specialisation over broad applicability
Come with clarity of thesis and founder capability, not just traction
Be open to 2048 leading and co-structuring your round from scratch
Apply to pitch competitions — direct access to fund
Focus on manufacturing/production bottlenecks in biotech and AI
Target protein manufacturing infrastructure — emerging thesis priority
Network with 2048 community at Boston/NYC events

Founder Don'ts

Don't pitch broad generalist platforms without domain specificity
Don't expect slow or opaque fundraising processes — match their speed
Don't rely on existing traction as your main signal; thesis and team matter more

Key GPs & Partners

2V
2048 Ventures Team
General Partner
thesis-drivenfast-movercommunity-builder
AK
Alexis Kold
Partner
founder-mentorthought-leaderoperational-focus

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Fund Overview

Fund Size$82M
Saves0

Key People

Alex Iskold

2048 Ventures TeamGeneral Partner
Alexis KoldPartner

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